Nanomedicine uses nanomaterials to improve disease prevention, detection, and treatment, resulting in hundreds of FDA-approved medical products. While nanomedicine has existed for several decades, new technological advances are pushing its boundaries. For example, Artificial Intelligence (AI) has revolutionized numerous industries. However, its use in nanomedicine has remained few and far between. One area in which AI has significantly improved nanomedicine is through implantable sensors. This invited talk will present research where implantable sensors, using AI, can learn from patients' responses to implants and predict future outcomes. Such implantable sensors incorporate AI, communicate with a handheld device, and reverse AI-predicted adverse events. Examples of AI implantable sensors used in orthopedics to inhibit implant infection and promote prolonged bone growth will be given. In vitro and in vivo experiments will demonstrate how AI can be used to our advantage in nanomedicine, especially implantable sensors. Lastly, this talk will summarize recent advances in nanomedicine to help human health and save the environment.